当前位置: X-MOL 学术Nat. Biomed. Eng. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Probing when dCas9 tolerates DNA mismatches
Nature Biomedical Engineering ( IF 28.1 ) Pub Date : 2023-12-22 , DOI: 10.1038/s41551-023-01172-5
Weihua Guan

Sensing changes in ionic current as barcoded DNA translocates through solid-state nanopores allows the study of how nucleotide sequences alter the DNA-binding specificity of the catalytically inactive Cas9 ribonucleoprotein complex.

中文翻译:

探索 dCas9 何时容忍 DNA 错配

当带条形码的 DNA 通过固态纳米孔易位时,感测离子电流的变化可以研究核苷酸序列如何改变催化失活的 Cas9 核糖核蛋白复合物的 DNA 结合特异性。
更新日期:2023-12-22
down
wechat
bug