The on-target off-tumour toxicities of T-cell-engaging bispecific antibodies in patients can be captured in intestinal organoids derived from the patients’ biopsied tissue and supplemented with immune cells.

中文翻译：

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评估双特异性抗体的毒性

患者体内 T 细胞参与双特异性抗体的脱靶毒性可以在源自患者活检组织并补充有免疫细胞的肠道类器官中捕获。