Combining a superoxide dismutase mimetic, avasopasem manganese, with stereotactic body radiation therapy may enable safe delivery of higher than standard radiation doses for patients with nonmetastatic, inoperable pancreatic adenocarcinoma. The phase Ib/II findings also suggest improved outcomes with avasopasem's addition, although the trial wasn't designed to compare arms and a larger study is needed.

中文翻译：

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针对非转移性 PDAC 的消融 SBRT

将超氧化物歧化酶模拟物 avasopasem 锰与立体定向放射治疗相结合，可以为非转移性、无法手术的胰腺癌患者安全地提供高于标准的放射剂量。 Ib/II 期研究结果还表明，添加 avasopasem 可以改善结果，尽管该试验的目的不是为了比较各组，并且需要进行更大规模的研究。