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Clonal expansion of CD8+ T cells in aged mice linked to pro-atherogenic phenotype
Nature Reviews Cardiology ( IF 49.6 ) Pub Date : 2023-12-08 , DOI: 10.1038/s41569-023-00981-0
Karina Huynh

In aged mice, but not young mice, with atherosclerosis, depletion of CD8+ T cells significantly reduces atherosclerotic lesion size and necrotic core area.

中文翻译:

老年小鼠 CD8+ T 细胞的克隆扩增与促动脉粥样硬化表型相关

在患有动脉粥样硬化的老年小鼠(而非年轻小鼠)中,CD8+ T 细胞的耗竭显着减少了动脉粥样硬化病变的大小和坏死核心区域。
更新日期:2023-12-08
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