Lactobacillus induced by irbesartan on spontaneously hypertensive rat contribute to its antihypertensive effect.,Journal of Hypertension

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Lactobacillus induced by irbesartan on spontaneously hypertensive rat contribute to its antihypertensive effect.
Journal of Hypertension ( IF 3.3 ) Pub Date : 2023-11-17 , DOI: 10.1097/hjh.0000000000003613
Yanling Xiong _{1,

2,

3,

4,

5} , Yanping He ₆ , Zhi Chen ₇ , Tianyuan Wu _{1,

3,

4,

5} , Yalan Xiong _{1,

3,

4,

5} , Yilei Peng _{1,

3,

4,

5} , Xuechun Yang _{1,

3,

4,

5} , Yujie Liu _{1,

3,

4,

5} , Jian Zhou _{1,

3,

4,

5} , Honghao Zhou _{1,

3,

4,

5} , Wei Zhang _{1,

3,

4,

5} , Yan Shu ₈ , Xiong Li ₆ , Qing Li _{1,

3,

4,

5}

Affiliation

Hypertension is linked to gut dysbiosis. Here, the impact of the angiotensin receptor antagonist irbesartan on the gut microbiota of spontaneously hypertensive rats (SHR) were investigated. In addition, we assessed their contribution to its antihypertensive effect.

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