FOXO3 longevity genotype attenuates the impact of hypertension on cerebral microinfarct risk.,Journal of Hypertension

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FOXO3 longevity genotype attenuates the impact of hypertension on cerebral microinfarct risk.
Journal of Hypertension ( IF 4.9 ) Pub Date : 2023-11-23 , DOI: 10.1097/hjh.0000000000003620
Kazuma Nakagawa _{1,

2,

3} , Randi Chen ₁ , G Webster Ross _{3,

4,

5,

6} , Timothy A Donlon _{1,

6,

7} , Richard C Allsopp ₈ , D Craig Willcox _{1,

9} , Brian J Morris _{1,

6,

10} , Bradley J Willcox _{1,

6} , Kamal H Masaki _{1,

6}

Affiliation

The G-allele of FOXO3 SNP rs2802292, which is associated with human resilience and longevity, has been shown to attenuate the impact of hypertension on the risk of intracerebral hemorrhage (ICH). We sought to determine whether the FOXO3 G-allele similarly attenuates the impact of hypertension on the risk of cerebral microinfarcts (CMI).

中文翻译：

FOXO3长寿基因型减弱了高血压对脑微梗塞风险的影响。

FOXO3 SNP rs2802292 的 G 等位基因与人类的恢复力和长寿相关，已被证明可以减弱高血压对脑出血 (ICH) 风险的影响。我们试图确定 FOXO3 G 等位基因是否同样可以减弱高血压对脑微梗塞 (CMI) 风险的影响。

更新日期：2023-11-23

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