Metastatic hepatocellular carcinoma (HCC) to the ovary is a rare and challenging histopathological diagnosis in the absence of the relevant clinical history. The differential diagnoses of a hepatoid tumor in the ovary are extensive, and correct diagnosis requires well-considered clinical-pathologic correlation. Familiarity with the diverse architectural patterns and immunophenotype of HCC is essential; however, even in the setting of known hepatic disease, a well-developed pseudoglandular pattern may be a convincing morphologic mimic of a primary surface epithelial ovarian malignancy. We describe a diagnostically challenging case of a 50-year-old woman with metastatic HCC exhibiting a prominent pseudoglandular pattern mimicking primary endometrioid adenocarcinoma, and an approach to overcome this important pitfall.

中文翻译：

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转移性肝细胞癌是 ER 阴性卵巢恶性肿瘤诊断评估中的一个重要但罕见的陷阱：病例报告。

在缺乏相关临床病史的情况下，卵巢转移性肝细胞癌（HCC）是一种罕见且具有挑战性的组织病理学诊断。卵巢肝样肿瘤的鉴别诊断很广泛，正确的诊断需要充分考虑临床病理相关性。熟悉 HCC 的不同结构模式和免疫表型至关重要；然而，即使在已知的肝脏疾病的情况下，发育良好的假腺体模式也可能是原发性表面上皮性卵巢恶性肿瘤的令人信服的形态学模拟。我们描述了一名患有转移性 HCC 的 50 岁女性的诊断具有挑战性的病例，该病例表现出模仿原发性子宫内膜样腺癌的显着假腺体模式，以及克服这一重要缺陷的方法。