Introduction

Indocyanine green (ICG) for axillary sentinel lymph node (SLN) detection in early breast cancer is at least equivalent to radioisotopic and/or colorimetric techniques. This procedure has not yet been recommended by learned societies in France. Following the recent drug approval of Infracyanin ® in this indication, we wished to study the use of ICG in France.

Methods

We conducted a web-based survey among members of multiple French breast cancer societies throughout November 2021. The survey assessed the profile of the respondent, the use or not of ICG for the detection of SLN in breast cancer, the technique used and the opinion of non-users and their expectations on the subject.

Results

Seventy-five surgeons participated. More than a third (37 %) have been using ICG for the detection of SLN in breast cancer for 2 to 3 years. Technique was highly variable. According to 82.1 % of the respondents, less than 20 procedures are necessary to master the use of ICG. The main advantage reported for this method is the reduction of organizational constraints. The obstacles to the use of the ICG are the near infra-red camera equipment, but also the lack of validation by the French guidelines. Among non-users, 83 % would like to develop this technique in their center and 72.3 % are interested in training on this subject.

Conclusion

This work highlights the need for French learned societies to take a stand on this issue but also the need to carry out studies on the technical aspects in order to standardise practices.

中文翻译：

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2021年法国吲哚菁绿荧光法乳腺癌前哨淋巴结活检的临床应用

 介绍

用于早期乳腺癌腋窝前哨淋巴结 (SLN) 检测的吲哚菁绿 (ICG) 至少相当于放射性同位素和/或比色技术。法国学术界尚未推荐该程序。继最近 Infrayanin ® 在该适应症上获得药物批准后，我们​​希望研究 ICG 在法国的使用。

 方法

我们于 2021 年 11 月对多个法国乳腺癌协会的成员进行了一项基于网络的调查。该调查评估了受访者的概况、是否使用 ICG 来检测乳腺癌中的 SLN、所使用的技术以及受访者的意见。非用户及其对此主题的期望。

 结果

七十五名外科医生参加了。超过三分之一 (37%) 已使用 ICG 检测乳腺癌中的 SLN 2 至 3 年。技术变化很大。 82.1%的受访者表示，掌握ICG的使用只需要不到20个程序。据报道，该方法的主要优点是减少了组织约束。 ICG使用的障碍是近红外摄像设备，而且缺乏法国指南的验证。在非用户中，83% 的人希望在他们的中心开发这项技术，72.3% 的人有兴趣接受该主题的培训。

 结论

这项工作强调了法国学术界需要在这个问题上表明立场，但也需要对技术方面进行研究，以标准化实践。