Candida auris, is an emerging fungal pathogen that can cause life-threatening infections in humans. Unlike many other Candida species that colonize the intestine, C. auris most efficiently colonizes the skin. Such colonization contaminates the patient’s environment and can result in rapid nosocomial transmission. In addition, this transmission can lead to outbreaks of systemic infections that have mortality rates between 40% and 60%. C. auris isolates resistant to all known classes of antifungals have been identified and as such, understanding the underlying biochemical mechanisms of how skin colonization initiates and progresses is critical to developing better therapeutic options. With this review, we briefly summarize what is known about horizontal transmission and current tools used to identify, understand, and control C. auris infections.

中文翻译：

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识别、研究和控制耳念珠菌的工具和技术


耳念珠菌，是一种新兴的真菌病原体，可引起人类危及生命的感染。与许多其他的不同念珠菌属定植于肠道的物种， C 。耳最有效地定植于皮肤。这种定植会污染患者的环境并可能导致快速的院内传播。此外，这种传播可能导致全身感染的爆发，死亡率在 40% 至 60% 之间。 C 。耳已鉴定出对所有已知类别的抗真菌药物具有耐药性的分离株，因此，了解皮肤定植如何启动和进展的潜在生化机制对于开发更好的治疗方案至关重要。通过这篇综述，我们简要总结了有关水平传输的知识以及用于识别、理解和控制的当前工具C 。耳感染。