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Analysis of 12 X-STRs loci in a population from southeastern Brazil
Forensic Science International: Genetics ( IF 3.1 ) Pub Date : 2023-11-02 , DOI: 10.1016/j.fsigen.2023.102974
Fernanda M Garcia 1 , Raquel S R Trabach 1 , Victor S Stange 2 , Bruno Cancian 1 , Alexia S S Zetum 1 , Matheus C Casotti 1 , Flavia I V Errera 1 , Elizeu F de Carvalho 3 , Débora D Meira 1 , Iuri D Louro 1
Affiliation  

Short tandem repeat (STR) markers on the X chromosome have a high potential for solving complex kinship analysis and individual identification cases. To achieve such purposes, allele and haplotype frequencies for the specific population are necessary. Nonetheless, such frequencies are not always available. Therefore, we obtained haplotypes from 520 unrelated males from four different geographic regions of Espírito Santo – Brazil, using the Investigator Argus X-12 kit. Forensic parameters for linked groups of four X-STR loci are reported. Genetic distance analyzes suggest that ES population is genetically closer to the Italian population and farther from the Mexican one, among the populations analyzed in this study.



中文翻译:

巴西东南部人群中 12 个 X-STR 位点的分析

X 染色体上的短串联重复 (STR) 标记在解决复杂的亲属关系分析和个体识别案例方面具有很高的潜力。为了实现这样的目的,特定人群的等位基因和单倍型频率是必要的。尽管如此,这样的频率并不总是可用。因此,我们使用 Investigator Argus X-12 试剂盒从来自巴西圣埃斯皮里图州四个不同地理区域的 520 名无关男性中获得了单倍型。报告了四个 X-STR 位点连锁组的法医参数。遗传距离分析表明,在本研究分析的人群中,ES 人群在遗传上更接近意大利人群,而远离墨西哥人群。

更新日期:2023-11-02
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