A window into the human immune system: comprehensive characterization of the complexity of antibody complementary-determining regions in functional antibodies,mAbs

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A window into the human immune system: comprehensive characterization of the complexity of antibody complementary-determining regions in functional antibodies
mAbs ( IF 5.3 ) Pub Date : 2023-10-24 , DOI: 10.1080/19420862.2023.2268255
Oscar Mejias-Gomez ₁ , Andreas V Madsen ₁ , Kerstin Skovgaard ₁ , Lasse E Pedersen ₁ , J Preben Morth ₁ , Timothy P Jenkins ₁ , Peter Kristensen ₂ , Steffen Goletz ₁

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The human immune system uses antibodies to neutralize foreign antigens. They are composed of heavy and light chains, both with constant and variable regions. The variable region has six hypervariab...

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