Homogentisic acid (HGA) is excreted in excessive amounts in the urine of patients with alkaptonuria, which is a hereditary metabolic disorder of phenylalanine and tyrosine. Therefore, the detection of HGA in urine is useful for the diagnosis of alkaptonuria. To evaluate the detection of HGA, we confirmed the color shift of HGA solutions and analyzed them by electrospray ionization mass spectrometry (ESI-MS).

中文翻译：

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电喷雾电离质谱法检测黑黑酸

尿黑酸尿症是一种遗传性苯丙氨酸和酪氨酸代谢紊乱症，尿黑酸尿症患者的尿液中会排出过量的尿黑酸 (HGA)。因此，尿液中HGA的检测有助于黑酸尿症的诊断。为了评估 HGA 的检测，我们确认了 HGA 溶液的色移，并通过电喷雾电离质谱 (ESI-MS) 对其进行了分析。