Currently, most men with infertility cannot be given an aetiology, which reflects a lack of knowledge around gamete production and how it is affected by genetics and the environment. A failure to recognize the burden of male infertility and its potential as a biomarker for systemic illness exists. The absence of such knowledge results in patients generally being treated as a uniform group, for whom the strategy is to bypass the causality using medically assisted reproduction (MAR) techniques. In doing so, opportunities to prevent co-morbidity are missed and the burden of MAR is shifted to the woman. To advance understanding of men’s reproductive health, longitudinal and multi-national centres for data and sample collection are essential. Such programmes must enable an integrated view of the consequences of genetics, epigenetics and environmental factors on fertility and offspring health. Definition and possible amelioration of the consequences of MAR for conceived children are needed. Inherent in this statement is the necessity to promote fertility restoration and/or use the least invasive MAR strategy available. To achieve this aim, protocols must be rigorously tested and the move towards personalized medicine encouraged. Equally, education of the public, governments and clinicians on the frequency and consequences of infertility is needed. Health options, including male contraceptives, must be expanded, and the opportunities encompassed in such investment understood. The pressing questions related to male reproductive health, spanning the spectrum of andrology are identified in the Expert Recommendation.

目前，大多数不育男性无法获得病因学信息，这反映出人们对配子产生及其如何受遗传和环境影响的了解缺乏。人们未能认识到男性不育症的负担及其作为全身性疾病生物标志物的潜力。由于缺乏此类知识，患者通常被视为统一的群体，其策略是使用医学辅助生殖 (MAR) 技术来绕过因果关系。这样做会错过预防合并症的机会，并且 MAR 的负担会转移到女性身上。为了增进对男性生殖健康的了解，纵向和跨国数据和样本收集中心至关重要。此类计划必须能够全面了解遗传学、表观遗传学和环境因素对生育力和后代健康的影响。需要定义 MAR 对受孕儿童的影响并可能改善其影响。该声明的本质是促进生育能力恢复和/或使用现有的侵入性最小的 MAR 策略的必要性。为了实现这一目标，必须严格测试方案并鼓励向个性化医疗迈进。同样，需要对公众、政府和临床医生进行有关不孕不育的频率和后果的教育。必须扩大包括男性避孕药具在内的健康选择，并了解此类投资所包含的机会。专家建议中确定了涉及男科学领域的男性生殖健康的紧迫问题。