In this study, we sought to clarify the patient traits and comorbidities that are associated with pressure injury recurrence following pressure injury reconstruction. An insurance claims database, PearlDiver, was used to conduct a retrospective cohort study. The two cohorts included patients who underwent pressure injury reconstruction without recurrence and patients who experienced recurrence with subsequent reconstruction. Multiple logistic regression analysis was used to identify risk factors for recurrence after reconstruction. Recurrence was associated with hypoalbuminemia (p < 0.05), paraplegia (p < 0.05), and osteomyelitis (p < 0.05). In patients with osteomyelitis, primary closure was associated with recurrence (p < 0.05) while flap reconstruction was not (p > 0.05). Osteomyelitis was not associated with recurrence after flap reconstruction. Prior to reconstruction, patients with osteomyelitis and hypoalbuminemia should have their nutrition and infection optimised.

中文翻译：

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重建后压疮复发的危险因素：国家数据库分析

在本研究中，我们试图阐明与压力性损伤重建后压力性损伤复发相关的患者特征和合并症。保险理赔数据库 PearlDiver 用于进行回顾性队列研究。这两个队列包括接受压力性损伤重建但未复发的患者和随后重建后复发的患者。使用多元逻辑回归分析来确定重建后复发的危险因素。复发与低白蛋白血症 ( p  < 0.05)、截瘫 ( p  < 0.05) 和骨髓炎 ( p  < 0.05)相关。在骨髓炎患者中，一期闭合与复发相关（p  <0.05），而皮瓣重建则不然（p  >0.05）。骨髓炎与皮瓣重建后的复发无关。在重建之前，骨髓炎和低蛋白血症患者应优化营养和感染。