Temporal and spatial effects on C-reactive protein's regulation of inducible nitric oxide synthase production in periodontal disease,Journal of Periodontology

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Temporal and spatial effects on C-reactive protein's regulation of inducible nitric oxide synthase production in periodontal disease
Journal of Periodontology ( IF 4.3 ) Pub Date : 2023-07-29 , DOI: 10.1002/jper.22-0529
Lingjie Li _{1,

2} , Lurong Jia _{1,

3} , Siyu Hou _{1,

2} , Tingwei Zhang _{1,

2} , Mengjiao Zhou _{1,

2} , Tao Chen _{1,

3} , Jinlin Song _{1,

2}

Affiliation

Inducible nitric oxide synthase (iNOS) is associated with inflammation and osteoclastic differentiation in periodontal disease. This study was conducted to compare the time-dependent variation in iNOS production between the gingiva and other periodontal tissues and to explore the potential association with C-reactive protein (CRP) in early periodontal disease.

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