Understanding the genetic basis of immunological processes and their overall dynamics under the influence of population immunogenetics and host-microbe interactions has been at the core of health and disease research. Our understanding of these dynamics has recently undergone a paradigm shift with the application of high-resolution single cell or spatial omics technologies that have facilitated a deeper understanding of healthy or diseased immune milieu. At Genes & Immunity, we wish to revamp the journal to cater to these trends and bring together researchers working at these multidisciplinary interfaces of immunology and genetics, with the aim of advancing fundamental and translational knowledge while revealing new immunotherapy or biomarker modalities.

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遗传学和免疫的动态界面：健康与疾病的未来前景

了解免疫过程的遗传基础及其在群体免疫遗传学和宿主-微生物相互作用影响下的整体动态一直是健康和疾病研究的核心。随着高分辨率单细胞或空间组学技术的应用，我们对这些动态的理解最近经历了范式转变，这些技术有助于更深入地了解健康或患病的免疫环境。在《Genes & Immunity》中，我们希望改进该期刊以迎合这些趋势，并将从事免疫学和遗传学多学科交叉领域研究的研究人员聚集在一起，目的是推进基础知识和转化知识，同时揭示新的免疫疗法或生物标志物模式。