Eccrine porocarcinoma is a rare cutaneous neoplasm, and rarer still in the anogenital region. In the vulva, the most common carcinoma by far is squamous cell carcinoma; however, eccrine porocarcinoma can arise at this site. As the distinction between porocarcinoma and squamous cell carcinoma has important prognostic implications at other cutaneous sites, it stands to reason that it may have these same implications in the vulva. We present a case of an eccrine porocarcinoma in the vulva of a 70-year-old woman that, in addition, showed sarcomatoid transformation. This tumor harbored human papillomavirus-18 DNA and mRNA, raising the question of the role of the oncogenic virus in sweat gland neoplasms of the vulva.

中文翻译：

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外阴小汗腺汗孔癌伴肉瘤样转化，一种新的人乳头瘤病毒相关恶性肿瘤？病例报告和文献综述。

小汗腺汗孔癌是一种罕见的皮肤肿瘤，在肛门生殖器区域更为罕见。在外阴，迄今为止最常见的癌症是鳞状细胞癌。然而，小汗腺汗孔癌可能发生在这个部位。由于毛孔癌和鳞状细胞癌之间的区别在其他皮肤部位具有重要的预后意义，因此理所当然地，它在外阴也可能具有相同的意义。我们介绍了一名 70 岁女性外阴小汗腺汗孔癌的病例，此外还表现出肉瘤样转化。该肿瘤含有人乳头瘤病毒 18 DNA 和 mRNA，引发了致癌病毒在外阴汗腺肿瘤中的作用问题。