Neuroendocrine tumours commonly metastasise to the liver, particularly those arising from the intestinal tract and pancreas. Whilst surgery offers the only approach with intent to cure, the vast majority of patients with neuroendocrine liver metastases are ineligible. Liver-directed interventional therapies seek to exploit the patho-anatomy of the blood supply of hepatic metastases to deliver therapy to liver deposits. This may involve percutaneous ablation, bland embolization, or the selective infusion of chemotherapeutics, targeted agents or radiolabelled embolic material. Retrospective case series evidence has characterised objective response rates, disease control rates, and longer-term outcomes associated with each approach. Recent advances in this field include ongoing comparative trials of different techniques, but more importantly, combinations of interventional liver-directed therapies and other systemic therapy in multimodal treatment concepts.

神经内分泌肿瘤通常转移至肝脏，特别是那些源自肠道和胰腺的肿瘤。虽然手术是唯一的治愈方法，但绝大多数患有神经内分泌肝转移的患者不符合治疗条件。以肝脏为导向的介入治疗寻求利用肝转移瘤血液供应的病理解剖学来对肝脏沉积物进行治疗。这可能涉及经皮消融、温和栓塞或选择性输注化疗药物、靶向药物或放射性标记的栓塞材料。回顾性病例系列证据描述了与每种方法相关的客观缓解率、疾病控制率和长期结果。该领域的最新进展包括正在进行的不同技术的比较试验，但更重要的是，在多模式治疗概念中将介入性肝脏定向治疗与其他全身治疗相结合。