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Associations of methadone and buprenorphine-naloxone doses with unregulated opioid use, treatment retention, and adverse events in prescription-type opioid use disorders: Exploratory analyses of the OPTIMA study
The American Journal on Addictions ( IF 3.860 ) Pub Date : 2023-06-12 , DOI: 10.1111/ajad.13439
Hamzah Bakouni 1 , Christina McAnulty 1, 2 , Ovidiu Tatar 1, 2 , M. Eugenia Socias 3, 4 , Bernard Le Foll 5, 6, 7, 8, 9 , Ron Lim 10 , Keith Ahamad 3, 11 , Didier Jutras‐Aswad 1, 2 ,
Affiliation  

Buprenorphine/naloxone (BUP-NX) and methadone are used to treat opioid use disorder (OUD), yet there is insufficient evidence on the impact of doses on interventions' effectiveness and safety when treating OUD attributable to other opioids than heroin.

中文翻译:

美沙酮和丁丙诺啡纳洛酮剂量与处方型阿片类药物使用障碍中不受管制的阿片类药物使用、治疗保留和不良事件的关联:OPTIMA 研究的探索性分析

丁丙诺啡/纳洛酮 (BUP-NX) 和美沙酮用于治疗阿片类药物使用障碍 (OUD),但在治疗海洛因以外的其他阿片类药物导致的 OUD 时,没有足够的证据表明剂量对干预措施的有效性和安全性的影响。
更新日期:2023-06-12
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