Phase III study of Phlai capsules in the treatment of allergic rhinitis: A randomized, double-blind, placebo-controlled trial.,Asian Pacific Journal of Allergy and Immunology

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Phase III study of Phlai capsules in the treatment of allergic rhinitis: A randomized, double-blind, placebo-controlled trial.
Asian Pacific Journal of Allergy and Immunology ( IF 5 ) Pub Date : 2023-06-11 , DOI: 10.12932/ap-090223-1541
Minh P Hoang _{1,

2,

3} , Kachorn Seresirikachorn _{1,

2} , Wirach Chitsuthipakorn _{4,

5} , Jompol Samuthpongtorn ₁ , Kajohnkiat Prasittivatechakool ₆ , Pongsakorn Tantilipikorn ₇ , Orapan Poachanukoon ₈ , Pornthep Kasemsiri ₉ , Virat Kirtsreesakul ₁₀ , Jesada Kanjanaumporn _{1,

2} , Songklot Aeumjaturapat _{1,

2} , Supinda Chusakul _{1,

2} , Kornkiat Snidvongs _{1,

2}

Affiliation

Department of Otolaryngology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Endoscopic Nasal and Sinus Surgery Excellent Center, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Department of Otolaryngology, Hue University of Medicine and Pharmacy, Hue University, Hue, Vietnam.
Center of Excellence in Otolaryngology-Head & Neck Surgery, Rajavithi Hospital, Bangkok, Thailand.
Department of Otolaryngology, College of Medicine, Rangsit University, Bangkok, Thailand.
Department of Otolaryngology, Phramongkutklao Hospital, Bangkok, Thailand.
Center of Research Excellence in Allergy & Immunology, Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Center of Excellence for Allergy, Asthma and Pulmonary Diseases, Department of Pediatrics, Thammasat University Hospital, Pathum Thani, Thailand.
Department of Otorhinolaryngology, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Department of Otolaryngology, Faculty of Medicine, Prince of Songkhla University, Hat Yai, Thailand.

Preclinical studies demonstrated anti-inflammatory effects of Zingiber montanum (J.König) Link ex Dietr.(Phlai). However, its clinical effect on allergic rhinitis (AR) is not evident.

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