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APPLICATIONS OF MULTICOMPONENT ASSEMBLY PROCESSES TO THE FACILE SYNTHESES OF DIVERSELY FUNCTIONALIZED NITROGEN HETEROCYCLES.
Heterocycles ( IF 0.8 ) Pub Date : 2012 , DOI: 10.3987/com-11-s(p)92
James R Donald 1 , Brett A Granger , Simon Hardy , James J Sahn , Stephen F Martin
Affiliation  

Several multicomponent assembly processes have been developed for the synthesis of intermediates that may be elaborated by a variety of cyclizations to generate a diverse array of highly functionalized heterocycles from readily-available starting materials. The overall approach enables the efficient preparation of libraries of small molecules derived from fused, privileged scaffolds.

中文翻译:

多组分组装工艺在多种功能化氮杂环化合物的简便合成中的应用。

已经开发了几种多组分组装工艺来合成中间体,这些中间体可以通过各种环化作用进行精细加工,以从容易获得的起始材料中生成各种高度官能化的杂环。整体方法能够有效地制备源自融合的特权支架的小分子文库。
更新日期:2017-01-31
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