Pregnancies following diagnosis of chronic lymphocytic leukemia (CLL) are rare events, mainly because the disease is typically diagnosed in the elderly. Literature on the topic is based only on case reports, and limited data are available on the influence of pregnancy on CLL course. In this retrospective study, we aimed to summarize the clinical and laboratory course of 10 women with CLL who became pregnant. None of the patients had significant changes in blood count during or after pregnancy or had complications such as infection, autoimmune phenomenon, or preeclampsia. Four out of 10 pregnancies were terminated with an early miscarriage. Following labor, 1 patient started anti-CLL treatment due to preexisting anemia, but none of the women required therapy during CLL progression during the first 2 years of follow-up. We conclude that based on our serial, pregnancy does not negatively impact on CLL course.

中文翻译：

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10 名被诊断患有慢性淋巴细胞白血病的女性的妊娠过程。

诊断出慢性淋巴细胞白血病 (CLL) 后怀孕的情况很少见，主要是因为该疾病通常在老年人中诊断出来。有关该主题的文献仅基于病例报告，关于妊娠对 CLL 病程影响的数据有限。在这项回顾性研究中，我们旨在总结 10 名怀孕的 CLL 女性的临床和实验室过程。没有患者在怀孕期间或怀孕后出现血细胞计数显着变化，也没有出现感染、自身免疫现象或先兆子痫等并发症。十分之四的妊娠因早期流产而终止。分娩后，1 名患者因先前存在贫血而开始抗 CLL 治疗，但在随访的前 2 年中，没有一位妇女在 CLL 进展期间需要治疗。我们的结论是，根据我们的系列研究，怀孕不会对 CLL 病程产生负面影响。