This study aimed to convert raw hide trimming waste into high-value collagenous products, thereby addressing solid waste problems and generating economic value. Processing parameters such as the effect of acid concentration on gelatin extraction and the effect of enzyme concentration/hydrolysis time on the extraction of collagen hydrolysate (CH) from raw trimming were optimized. These process parameters were then integrated to extract gelatin and CH sequentially from raw trimming wastes. The process produced ∼55% as gelatin with a gel strength of 230 ± 8 g and a molecular weight fraction ranged between 50 and 200 kDa. The remaining collagenous matrix (after gelatin extraction) was recovered as CH with a yield of 97% (based on available collagen) consisting of molecular weight fractions ranging from 598.31 to 6236.12 Da. The produced gelatin and CH met the requirements for high-value applications in the food, cosmetic, and pharmaceutical industries. The study demonstrates an efficient process for utilizing collagenous proteins from raw hide trimmings and valorizing tannery solid wastes.

这项研究旨在将生皮修边废物转化为高价值的胶原产品，从而解决固体废物问题并产生经济价值。酸浓度对明胶提取的影响以及酶浓度/水解时间对胶原蛋白水解物提取的影响等工艺参数(CH) 来自原始修剪的优化。然后整合这些工艺参数，从原始修整废料中依次提取明胶和 CH。该过程产生约 55% 的明胶，凝胶强度为 230 ± 8 g，分子量分数在 50 至 200 kDa 之间。剩余的胶原基质（明胶提取后）以 CH 形式回收，产率为 97%（基于可用胶原蛋白），由分子量范围为 598.31 至 6236.12 Da 的部分组成。生产的明胶和 CH 满足食品、化妆品和制药行业高价值应用的要求。该研究展示了一种利用生皮边角料中的胶原蛋白和使制革厂固体废物增值的有效方法。