Importance Mounting evidence supports the role of spiritual, existential, religious, and theological components in mediating psychedelic-assisted therapy, yet integration of these elements into the clinical setting is lagging. Observations Although psychedelic-assisted therapy commonly produces spiritually, existentially, religiously, or theologically relevant experiences for patients, these have not been systematically integrated into the psychotherapies that accompany therapeutic uses of psychedelics. As a key feature and potential mediator of therapeutic effects, evidence-based psychedelic-assisted therapies should include these topics in the treatment model. Research across multiple diagnostic targets and treatment contexts suggests that spiritually integrated psychotherapies are effective, feasible, and produce add-on benefits in spiritually, existentially, religiously, and theologically relevant outcomes, which are particularly germane to psychedelics. Established standards in spiritually integrated psychotherapy may be fruitfully applied to psychedelic-assisted therapy. Objectives for spiritually, existentially, religiously, and theologically integrated psychedelic-assisted therapy based on these standards and informed by considerations specific to psychedelics are recommended. Conclusions and Relevance Spiritual, existential, religious, and theological topics' integration in psychedelic-assisted therapy is needed to ensure culturally competent, evidence-based treatment aligned with the highest standards of clinical care. Neglecting to address these topics can detract from cultural competence, contribute to risks for patients, and potentially undermine treatment success.

中文翻译：

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在迷幻辅助治疗中整合精神、存在、宗教和神学成分的重要性。

重要性越来越多的证据支持精神、存在、宗教和神学成分在介导迷幻辅助治疗中的作用，但将这些元素整合到临床环境中却滞后。观察虽然迷幻药辅助治疗通常会为患者带来精神上、存在主义、宗教上或神学上的相关体验，但这些体验尚未系统地整合到伴随迷幻药治疗用途的心理治疗中。作为治疗效果的关键特征和潜在调节因素，循证迷幻辅助疗法应将这些主题纳入治疗模型中。跨多个诊断目标和治疗背景的研究表明，精神整合心理治疗是有效、可行的，并在精神上、与存在、宗教和神学相关的结果，这与致幻剂尤其密切相关。精神整合心理治疗的既定标准可以有效地应用于迷幻辅助治疗。建议基于这些标准并根据迷幻剂的具体考虑因素制定精神上、存在主义、宗教上和神学上综合迷幻剂辅助治疗的目标。结论和相关性 精神、存在主义、宗教和神学主题需要整合到迷幻辅助治疗中，以确保文化上合格的、循证的治疗与临床护理的最高标准保持一致。忽视这些话题可能会损害文化能力，给患者带来风险，并可能损害治疗的成功。