In this study, in-situ preparation of copper nanoparticles under sonoheating conditions followed by coating on commercial polyester fabric is reported. Through the self-assembly interaction of thiol groups and copper nanoparticles, the modified polyhedral oligomeric silsesquioxanes (POSS) was deposited on the fabric's surface. In the next step, radical thiol–ene click reactions were implemented to create more layers of POSSs. Subsequently, the modified fabric was applied for sorptive thin film extraction of non-steroidal anti-inflammatory drugs (NSAIDs) including naproxen, ibuprofen, diclofenac, and mefenamic acid from urine samples, followed by high-performance liquid chromatography equipped with a UV detector. The morphology of the prepared fabric phase was characterized by scanning electron microscopy, water angle contact, energy dispersive spectrometry mapping, analysis of nitrogen adsorption-desorption isotherms, and attenuated total reflectance Fourier transform infrared spectroscopy. The significant extraction parameters, including the acidity of the sample solution, desorption solvent and its volume, extraction time, and desorption time, were investigated using the one-variable-at-a-time approach. Under the optimal condition, NSAIDs' detection limit was 0.3–1 ng mL⁻¹ with a wide linear range of 1–1000 ng mL⁻¹. The recovery values were between 94.0% and 110.0%, with relative standard deviations of less than 6.3%. The prepared fabric phase exhibited acceptable repeatability, stability, and sorption property toward NSAIDs in urine samples.

本研究中，原位报道了在超声波加热条件下制备铜纳米粒子，然后在商业聚酯织物上进行涂层。通过硫醇基团和铜纳米粒子的自组装相互作用，改性多面体低聚倍半硅氧烷 (POSS) 沉积在织物表面。在下一步中，实施自由基硫醇-烯点击反应以创建更多层的 POSS。随后，将改性织物应用于尿样中萘普生、布洛芬、双氯芬酸和甲芬那酸等非甾体类抗炎药 (NSAIDs) 的吸附薄膜提取，然后采用配备 UV 检测器的高效液相色谱法。制备的织物相的形貌通过扫描电子显微镜、水角接触、能量色散谱图、分析氮气吸附-脱附等温线和衰减全反射傅里叶变换红外光谱。使用一次一个变量的方法研究了重要的提取参数，包括样品溶液的酸度、解吸溶剂及其体积、提取时间和解吸时间。在最佳条件下，NSAIDs 的检测限为 0.3–1 ng·mL^{−1具有 1–1000 ng mL −1}的宽线性范围。回收率介于 94.0% 和 110.0% 之间，相对标准偏差小于 6.3%。制备的织物相表现出可接受的重复性、稳定性和对尿样中 NSAIDs 的吸附性能。