Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used globally to treat and prevent illness. Biosolids change physico-chemical characteristics of soil and can affect the mobility of NSAIDs. A field-based lysimeter study evaluated the effect of three rates (0, 7, and 28 Mg ha⁻¹) of alkaline treated biosolids (ATB) on the leaching potential of naproxen (NPX), ibuprofen (IBF), and ketoprofen (KTF) over 34 days in a sandy loam textured soil. Although all three NSAIDs in the lysimeter cells vertically migrated to deeper soil depths after spiking, the sum of all NPX, IBF, and KTF detected in the leachate samples from all treatments were only 0.03%, 0.02%, and 0.04% of the initial spiking mass to the surface soil, respectively. A mass balance analysis indicated a low accumulation of these compounds in the soil at the end of the study (Day 34) from all treatments with only 4.8%, 0.5%, and 0.7% of initial spiked NPX, IBF, and KTF, respectively. Application of ATB significantly increased soil pH and organic matter (OM) content of the soils but did not impact retention of the compounds in the soil profile. Overall, all three NSAIDs in the present study presented low mobility in the loamy sand textured agricultural soil.

非甾体类抗炎药 (NSAID) 在全球范围内广泛用于治疗和预防疾病。生物固体会改变土壤的物理化学特性，并会影响非甾体抗炎药的流动性。基于现场的蒸渗仪研究评估了三种速率（0、7 和 28 Mg ha ⁻¹) 碱处理的生物固体 (ATB) 对萘普生 (NPX)、布洛芬 (IBF) 和酮洛芬 (KTF) 在沙壤土质地土壤中 34 天的浸出潜力的影响。尽管渗漏计池中的所有三种 NSAIDs 在加标后都垂直迁移到更深的土壤深度，但在所有处理的渗滤液样品中检测到的所有 NPX、IBF 和 KTF 的总和仅为初始加标的 0.03%、0.02% 和 0.04%质量到表层土壤，分别。质量平衡分析表明，在研究结束时（第 34 天），所有处理的这些化合物在土壤中的积累量很低，初始添加的 NPX、IBF 和 KTF 分别仅为 4.8%、0.5% 和 0.7%。ATB 的应用显着增加了土壤的土壤 pH 值和有机质 (OM) 含量，但不影响土壤剖面中化合物的保留。全面的，