Viruses cause various diseases in humans, and pose serious health risks to individuals and populations worldwide. As a result, various diagnostic procedures and methods have been developed to prevent, manage, and reduce the burden of viral diseases, each with its own benefits and drawbacks. Among these, paper-based diagnostic chips are becoming increasingly common because of their speed, accuracy, convenience, and economical and environmental friendliness. These paper-based diagnostic tests have ideal point-of-care (POC) diagnostic applications, particularly in personalized healthcare. Paper-based diagnostics have emerged as innovative and low-cost solutions for diagnosing viral diseases in remote and underdeveloped regions where traditional diagnostic methods are not readily available. These tests are easy to use, require minimal equipment, and can be performed by nonspecialized personnel, making them accessible even in resource-constrained settings. In this review, we discuss recent developments in paper-based diagnostic chips, the importance of improved methods for identifying viral pathogens, drawbacks of traditional detection techniques, and challenges and prospects of paper-based diagnostic chips for the detection of viruses.

病毒会引起人类各种疾病，并对全世界的个人和人群构成严重的健康风险。因此，人们开发了各种诊断程序和方法来预防、管理和减轻病毒性疾病的负担，每种程序和方法都有其自身的优点和缺点。其中，纸质诊断芯片因其快速、准确、方便、经济、环保等优点而变得越来越普遍。这些纸质诊断测试具有理想的护理点 (POC) 诊断应用，特别是在个性化医疗保健领域。纸质诊断已成为在传统诊断方法不易获得的偏远和欠发达地区诊断病毒性疾病的创新且低成本的解决方案。这些测试易于使用，需要最少的设备，并且可以由非专业人员执行，即使在资源有限的环境中也可以进行操作。在这篇综述中，我们讨论了纸基诊断芯片的最新发展、改进病毒病原体识别方法的重要性、传统检测技术的缺点以及纸基诊断芯片用于病毒检测的挑战和前景。