The current systematic review sought to identify quantitative empirical studies that focused on the transdiagnostic factors of intolerance of uncertainty, emotional dysregulation and rumination, and their relation with depression and post-traumatic stress disorder (PTSD). The overall research aim was to examine the relationship between these transdiagnostic factors and their relation with depression and PTSD symptoms. The systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines. Out of the 768 articles initially identified, 55 met the inclusion criteria for the current review. The results determined that intolerance of uncertainty is indirectly related to depression and PTSD symptoms, mainly through other factors including emotion dysregulation and rumination. Additionally, emotional dysregulation is a significant predictor of both depression and PTSD symptoms. Rumination is a robust factor related to depression and PTSD symptoms, this relationship was significant in cross-sectional and longitudinal studies. This review provides evidence on the transdiagnostic factors of intolerance of uncertainty, emotional dysregulation and rumination in the relationship with depression and PTSD symptoms.

当前的系统综述旨在确定定量实证研究，重点关注不能容忍不确定性、情绪失调和沉思等跨诊断因素，及其与抑郁症和创伤后应激障碍（PTSD）的关系。总体研究目的是检查这些跨诊断因素之间的关系及其与抑郁症和创伤后应激障碍症状的关系。系统评价是根据系统评价和荟萃分析的首选报告项目（PRISMA）指南进行的。在最初确定的 768 篇文章中，有 55 篇符合当前审查的纳入标准。结果确定，不能容忍不确定性与抑郁和创伤后应激障碍症状间接相关，主要是通过情绪失调和沉思等其他因素。此外，情绪失调是抑郁症和创伤后应激障碍症状的重要预测因素。沉思是与抑郁和创伤后应激障碍症状相关的一个强有力的因素，这种关系在横断面和纵向研究中都很重要。这篇综述提供了关于不能容忍不确定性、情绪失调和沉思等跨诊断因素与抑郁症和创伤后应激障碍症状的关系的证据。