Biofuels are a type of renewable energy that can become more vital in our lives. There are several advantages to switching to alternative biofuels and green techniques for producing these biofuels from biomass feedstock. 5-Hydroxymethylfurfural (HMF) is a potential precursor for biofuel and is synthesized from biomass sources. DMSO is specifically known as the most effective solvent for the conversion of biomass into HMF, leading to high yields. Due to the high miscibility of DMSO with various organic solvents, isolating HMF from the reaction mixture continues to be complicated. The use of a deep eutectic solvent (DES) in the biomass conversion process is attracting much attention. We have developed the synthesis of HMF from glucose, fructose, and cellulose using metal chloride in a [DMSO][CholineCl] deep eutectic solvent, which was easily obtained by combining DMSO and choline chloride. The yields of HMF under optimal conditions from glucose, fructose, and cellulose were 40%, 93%, and 15%, respectively. The HMF product can be isolated from [DMSO][CholineCl] deep eutectic solvent mixture by the liquid-liquid extraction using organic solvents with high purity.

生物燃料是一种可再生能源，可以在我们的生活中变得更加重要。转向替代生物燃料和从生物质原料生产这些生物燃料的绿色技术有几个优势。5-羟甲基糠醛 (HMF) 是一种潜在的生物燃料前体，由生物质资源合成。DMSO 特别被认为是将生物质转化为 HMF 的最有效溶剂，可实现高产率。由于 DMSO 与各种有机溶剂的高混溶性，从反应混合物中分离 HMF 仍然很复杂。在生物质转化过程中使用低共熔溶剂 (DES) 引起了广泛关注。我们开发了在 [DMSO][CholineCl] 低共熔溶剂中使用金属氯化物从葡萄糖、果糖和纤维素合成 HMF，这很容易通过结合 DMSO 和氯化胆碱获得。在最佳条件下，葡萄糖、果糖和纤维素的 HMF 产率分别为 40%、93% 和 15%。HMF 产品可以通过使用高纯度有机溶剂的液-液萃取从 [DMSO][CholineCl] 低共熔溶剂混合物中分离出来。