Endothelial-lined valves assure unidirectional flow in the lymphatic system. In this issue, Saygili Demir et al. (2023. J. Cell Biol.https://doi.org/10.1083/jcb.202207049) demonstrate how continuous repair of these valves occur, beginning with mTOR-activated cell replication in valve sinuses, and followed by cell migration to cover the valve surface.

中文翻译：

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利用 escaLEC-TOR 促进瓣膜健康

内皮衬里的瓣膜确保淋巴系统中的单向流动。在本期中，Saygili Demir 等人。(2023. J. Cell Biol.https://doi.org/10.1083/jcb.202207049) 演示了这些瓣膜如何进行持续修复，从 mTOR 激活的瓣膜窦中的细胞复制开始，然后细胞迁移以覆盖瓣膜阀门表面。