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Isosorbide Mononitrate and Cilostazol Treatment in Patients With Symptomatic Cerebral Small Vessel Disease: The Lacunar Intervention Trial-2 (LACI-2) Randomized Clinical Trial.
JAMA Neurology ( IF 20.4 ) Pub Date : 2023-05-24 , DOI: 10.1001/jamaneurol.2023.1526 Joanna M. Wardlaw 1 , Lisa J. Woodhouse 2 , Iris I. Mhlanga 2 , Katherine Oatey 3 , Anna K. Heye 3 , John Bamford 4 , Vera Cvoro 1, 5 , Fergus N. Doubal 1 , Timothy England 2 , Ahamad Hassan 4 , Alan Montgomery 6 , John T. O’Brien 7 , Christine Roffe 8 , Nikola Sprigg 2 , David J. Werring 9 , Philip M. Bath 2 , Colin Baigent 10 , Gary Ford 10 , Jonathan Emberson 10 , Alison Murray 10 , A Ross Naylor 10 , Kailash Krishnan 10 , Jesse Dawson 10 , Chris Patterson 10 , German Guzman Gutierrez 10 , Stephen Makin 10 , Usman Khan 10 , Laszlo Sztriha 10 , Thomas Booth 10 , Amanathan Kirthivasan 10 , Anwar Ijaz 10 , Kirsty Harkness 10 , Sevasti Ispoglou 10 , Nigel Smyth 10 , Aravinth Sivagnanaratnam 10 , David Cohen 10 , Lakshmanan Sekaran 10 , Dinesh Chadha 10 , Nasar Ahmad 10 , Pratap Rana 10 , Malik Hussain 10 , Nic Weir 10 , Thomas Harrison 10 , Salim Elyas 10 ,
JAMA Neurology ( IF 20.4 ) Pub Date : 2023-05-24 , DOI: 10.1001/jamaneurol.2023.1526 Joanna M. Wardlaw 1 , Lisa J. Woodhouse 2 , Iris I. Mhlanga 2 , Katherine Oatey 3 , Anna K. Heye 3 , John Bamford 4 , Vera Cvoro 1, 5 , Fergus N. Doubal 1 , Timothy England 2 , Ahamad Hassan 4 , Alan Montgomery 6 , John T. O’Brien 7 , Christine Roffe 8 , Nikola Sprigg 2 , David J. Werring 9 , Philip M. Bath 2 , Colin Baigent 10 , Gary Ford 10 , Jonathan Emberson 10 , Alison Murray 10 , A Ross Naylor 10 , Kailash Krishnan 10 , Jesse Dawson 10 , Chris Patterson 10 , German Guzman Gutierrez 10 , Stephen Makin 10 , Usman Khan 10 , Laszlo Sztriha 10 , Thomas Booth 10 , Amanathan Kirthivasan 10 , Anwar Ijaz 10 , Kirsty Harkness 10 , Sevasti Ispoglou 10 , Nigel Smyth 10 , Aravinth Sivagnanaratnam 10 , David Cohen 10 , Lakshmanan Sekaran 10 , Dinesh Chadha 10 , Nasar Ahmad 10 , Pratap Rana 10 , Malik Hussain 10 , Nic Weir 10 , Thomas Harrison 10 , Salim Elyas 10 ,
Affiliation
Cerebral small vessel disease (cSVD) is a common cause of stroke (lacunar stroke), is the most common cause of vascular cognitive impairment, and impairs mobility and mood but has no specific treatment.
中文翻译：
有症状的脑小血管病患者的单硝酸异山梨酯和西洛他唑治疗：腔隙干预试验 2 (LACI-2) 随机临床试验。
脑小血管病 (cSVD) 是中风（腔隙性中风）的常见原因，是血管性认知障碍的最常见原因，会损害行动能力和情绪，但没有具体的治疗方法。
更新日期：2023-05-24
中文翻译：
有症状的脑小血管病患者的单硝酸异山梨酯和西洛他唑治疗：腔隙干预试验 2 (LACI-2) 随机临床试验。
脑小血管病 (cSVD) 是中风（腔隙性中风）的常见原因，是血管性认知障碍的最常见原因，会损害行动能力和情绪，但没有具体的治疗方法。
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