In patients with severe acute alcohol-related hepatitis not responding to medical therapy, early liver transplantation (LT) represents the only effective therapy and, when performed within strict and well-defined protocols, it is associated with a clear survival benefit and acceptable rates of return to alcohol use after transplantation. However, there is still high variability in access to LT for patients with severe alcohol-related hepatitis, mainly due to a persistent overemphasis in the pre-LT evaluation on duration of pre-transplant abstinence and the stigma that patients with alcohol-related liver disease often experience, leading to marked inequity of access to this potentially lifesaving procedure and negative health outcomes. Therefore, there is an increasing need for prospective multicentre studies focusing on pre-transplant selection practices and on better interventions to treat alcohol use disorder after LT.

对于对药物治疗无反应的严重急性酒精相关性肝炎患者，早期肝移植（LT）是唯一有效的治疗方法，并且当在严格且明确的方案中进行时，它与明显的生存获益和可接受的肝移植率相关。移植后恢复饮酒。然而，严重酒精相关性肝炎患者接受 LT 的情况仍然存在很大差异，这主要是由于 LT 前评估持续过分强调移植前禁欲时间以及酒精相关性肝病患者的耻辱感。经常经历，导致获得这种可能挽救生命的程序的机会明显不平等以及负面的健康结果。所以，