Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
Silencing tau to treat early Alzheimer’s disease
Nature Medicine ( IF 58.7 ) Pub Date : 2023-05-17 , DOI: 10.1038/s41591-023-02357-w Peter A Ljubenkov 1 , Gil D Rabinovici 1, 2
Nature Medicine ( IF 58.7 ) Pub Date : 2023-05-17 , DOI: 10.1038/s41591-023-02357-w Peter A Ljubenkov 1 , Gil D Rabinovici 1, 2
Affiliation
An antisense oligonucleotide therapy substantially reduced tau expression in a phase 1b trial; whether this translates to clinical improvement remains to be seen, but it could have far-reaching implications for neurodegenerative diseases more broadly.
中文翻译:
沉默 tau 蛋白可治疗早期阿尔茨海默病
在 1b 期试验中,反义寡核苷酸疗法显着降低了 tau 表达;这是否会转化为临床改善还有待观察,但它可能对更广泛的神经退行性疾病产生深远的影响。
更新日期:2023-05-18
中文翻译:
沉默 tau 蛋白可治疗早期阿尔茨海默病
在 1b 期试验中,反义寡核苷酸疗法显着降低了 tau 表达;这是否会转化为临床改善还有待观察,但它可能对更广泛的神经退行性疾病产生深远的影响。