We characterized cancer cells, immune responses and the microbiota composition in a cohort of primary colon cancers. Multi-omic analyses defined parameters associated with favorable prognosis, including a score that captured the intratumoral immune response and a specific microbiome signature. This data repository (atlas and compass of immune–cancer–microbiome interactions (AC-ICAM)) is publicly available.

中文翻译：

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免疫-微生物群相互作用影响结肠癌患者的预后

我们对一组原发性结肠癌中的癌细胞、免疫反应和微生物群组成进行了表征。多组学分析定义了与良好预后相关的参数，包括捕获瘤内免疫反应的评分和特定的微生物组特征。该数据存储库（免疫-癌症-微生物组相互作用图谱和指南针 (AC-ICAM)）是公开可用的。