A One-Pot Approach to Multi-Substituted Fused Aziridines: Formal Intermolecular [2+1] Cycloaddition Reaction between Saccharin-Derived Cyclic Ketimines and Sulfur Ylides,European Journal of Organic Chemistry

当前位置： X-MOL 学术 › Eur. J. Org. Chem. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

A One-Pot Approach to Multi-Substituted Fused Aziridines: Formal Intermolecular [2+1] Cycloaddition Reaction between Saccharin-Derived Cyclic Ketimines and Sulfur Ylides
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2023-05-16 , DOI: 10.1002/ejoc.202300300
Chao Lin ₁ , Mao-Chang Wang ₂ , Peng Wei ₂ , Qi Xing ₂ , Chen-He Liu ₂

Affiliation

Synthesis of aziridines was accomplished by a formal intermolecular [2+1] cycloaddition reaction of saccharin-derived cyclic ketimines with sulfur ylides. This methodology features high atom-economy, broad substrate scope and an operationally simple procedure, affording the aziridines with excellent yields and diastereoselectivity (>20 : 1 dr).

中文翻译：

多取代稠合氮丙啶的一锅法：糖精衍生的环状酮亚胺与硫叶立德之间的正式分子间 [2+1] 环加成反应

氮丙啶的合成是通过糖精衍生的环状酮亚胺与硫叶立德的正式分子间[2+1]环加成反应完成的。该方法具有高原子经济性、广泛的底物范围和操作简单的程序，使氮丙啶具有优异的产率和非对映选择性（> 20 : 1 dr）。

更新日期：2023-05-16

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11