Neoadjuvant immunotherapy for melanoma is now ready for clinical practice,Nature Medicine

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Neoadjuvant immunotherapy for melanoma is now ready for clinical practice
Nature Medicine ( IF 58.7 ) Pub Date : 2023-05-16 , DOI: 10.1038/s41591-023-02336-1
Claus Garbe ₁ , Reinhard Dummer _{2,

3} , Teresa Amaral ₁ , Rodabe N Amaria ₄ , Paolo A Ascierto ₅ , Elizabeth M Burton ₄ , Brigitte Dreno ₆ , Alexander M M Eggermont _{7,

8} , Axel Hauschild ₉ , Christoph Hoeller ₁₀ , Roland Kaufmann ₁₁ , Celeste Lebbe ₁₂ , Mario Mandala ₁₃ , Alexander M Menzies _{14,

15,

16} , David Moreno ₁₇ , Olivier Michielin ₁₈ , Paul Nathan ₁₉ , Sapna P Patel ₄ , Caroline Robert ₂₀ , Dirk Schadendorf _{21,

22} , Paul C Lorigan ₂₃ , Richard A Scolyer _{14,

15,

16} , Hussein A Tawbi ₄ , Bart A van de Wiel ₂₄ , Christian Blank _{25,

26} , Georgina V Long _{14,

15,

16}

Affiliation

Centre for Dermatooncology, Department of Dermatology, Eberhard Karls University, Tuebingen, Germany.
Department of Dermatology, University Hospital Zürich (USZ), Zürich, Switzerland.
Faculty of Medicine, University of Zürich (UZH), Zürich, Switzerland.
Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Department of Skin Cancer, Cancer Immunotherapy and Development Therapeutics, Instituto Nazionale Tumouri IRCCS Fondazione G. Pascale, Napoli, Italy.
Nantes University, Nantes, France.
Faculty of Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
Comprehensive Cancer Centre Munich of the Technical University Munich and the Ludwig Maximilians University, Munich, Germany.
Department of Dermatology, University Hospital Schleswig-Holstein (UKSH), Kiel, Germany.
Department of Dermatology, Medical University of Vienna, Vienna, Austria.
Department of Dermatology, Venerology and Allergology, Frankfurt University Hospital, Frankfurt, Germany.
Université Paris Cite, AP-HP Department of Dermatology, Hôpital Saint-Louis Paris, Paris, France.
Department of Surgery and Medicine, Unit of Medical Oncology, University of Perugia, Perugia, Italy.
Melanoma Institute Australia, The University of Sydney, Sydney, New South Wales, Australia.
Royal North Shore and Mater Hospitals, Sydney, New South Wales, Australia.
Faculty of Medicine & Health, The University of Sydney, Sydney, NSW, Australia.
Medical & Surgical Dermatology Service, Hospital Universitario Virgen Macarena, Sevilla, Spain.
Department of Medical Oncology, Lausanne University Hospital, Lausanne, Switzerland.
Mount Vernon Cancer Centre, Northwood, UK.
Department of Medical Oncology, Gustave Roussy and Paris-Saclay University, Villejuif, France.
Department of Dermatology, University Hospital Essen, Essen, Germany.
German Cancer Consortium, Heidelberg Partner Site Essen, Essen, Germany.
University of Manchester, Manchester, UK.
Department of Pathology, Netherlands Cancer Institute (NKI), Amsterdam, The Netherlands.
Department of Medical Oncology, Netherlands Cancer Institute (NKI), Amsterdam, The Netherlands.
Leiden University Medical Centre (LUMC), Leiden, The Netherlands.

Individuals with cutaneous melanoma who are treated with neoadjuvant immunotherapy show a substantial improvement; this should be incorporated into standard care.

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