The CanScreen5 project is a global cancer screening data repository that aims to report the status and performance of breast, cervical and colorectal cancer screening programs using a harmonized set of criteria and indicators. Data collected mainly from the Ministry of Health in each country underwent quality validation and ultimately became publicly available through a Web-based portal. Until September 2022, 84 participating countries reported data for breast (n = 57), cervical (n = 75) or colorectal (n = 51) cancer screening programs in the repository. Substantial heterogeneity was observed regarding program organization and performance. Reported screening coverage ranged from 1.7% (Bangladesh) to 85.5% (England, United Kingdom) for breast cancer, from 2.1% (Côte d’Ivoire) to 86.3% (Sweden) for cervical cancer, and from 0.6% (Hungary) to 64.5% (the Netherlands) for colorectal cancer screening programs. Large variability was observed regarding compliance to further assessment of screening programs and detection rates reported for precancers and cancers. A concern is lack of data to estimate performance indicators across the screening continuum. This underscores the need for programs to incorporate quality assurance protocols supported by robust information systems. Program organization requires improvement in resource-limited settings, where screening is likely to be resource-stratified and tailored to country-specific situations.

CanScreen5 项目是一个全球癌症筛查数据存储库，旨在使用一套统一的标准和指标来报告乳腺癌、宫颈癌和结直肠癌筛查项目的状态和绩效。主要从各国卫生部收集的数据经过质量验证，并最终通过基于网络的门户公开提供。截至 2022 年 9 月，84 个参与国家在存储库中报告了乳腺癌 ( n = 57)、宫颈癌 ( n = 75) 或结直肠癌 ( n = 51) 癌症筛查项目的数据。在项目组织和绩效方面观察到显着的异质性。报告的乳腺癌筛查覆盖率范围为 1.7%（孟加拉国）至 85.5%（英国、英国），宫颈癌筛查覆盖率范围为 2.1%（科特迪瓦）至 86.3%（瑞典），宫颈癌筛查覆盖率范围为 0.6%（匈牙利）至64.5%（荷兰）支持结直肠癌筛查计划。在对筛查计划的进一步评估以及报告的癌前期和癌症检出率的依从性方面观察到了很大的变异性。令人担忧的是缺乏数据来估计整个筛选过程中的绩效指标。这强调了项目需要纳入由强大的信息系统支持的质量保证协议。计划组织需要在资源有限的环境中进行改进，在这种情况下，筛选可能会按资源分层并根据国家具体情况进行定制。