Apheresis is an automated process to separate the whole blood of a patient or a donor, collect or remove specific blood components, and return the remaining back to the individual. Apheresis is an integral part of blood and marrow transplantation and has been increasingly utilized in novel cellular therapies for a variety of blood disorders. This review uses clinical cases to highlight the multiple roles of apheresis in the care of adult leukaemia patients, including therapeutic leukapheresis in hyperleukocytosis, mobilized peripheral blood hematopoietic progenitor cell collection in donors, mononucleated cell collection in preparation of donor lymphocyte infusion or chimeric antigen receptor T cells manufacture, and extracorporeal photopheresis in the treatment of graft versus host diseases.

单采术是一种自动化过程，用于分离患者或捐赠者的全血，收集或去除特定的血液成分，并将剩余的血液返回给个人。单采术是血液和骨髓移植的一个组成部分，并且已越来越多地应用于治疗各种血液疾病的新型细胞疗法中。本综述使用临床案例来强调单采术在成人白血病患者护理中的多重作用，包括白细胞增多症的治疗性白细胞分离术、捐献者的动员外周血造血祖细胞采集、单核细胞采集以准备供体淋巴细胞输注或嵌合抗原受体T细胞制造和体外光采术治疗移植物抗宿主疾病。