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Arginyl-tRNA synthetase in inflammation
Nature Cell Biology ( IF 17.3 ) Pub Date : 2023-04-14 , DOI: 10.1038/s41556-023-01090-3
Jie Chen 1
Affiliation  

The house-keeping aminoacyl-tRNA synthetases are increasingly recognized for their regulatory roles beyond protein synthesis. Research now uncovers a function of nuclear arginyl-tRNA synthetase in the regulation of alternative mRNA splicing through SRRM2 in response to inflammation and decreased arginine levels.

中文翻译:

炎症中的精氨酰-tRNA 合成酶

管家氨酰-tRNA 合成酶因其在蛋白质合成之外的调节作用而越来越受到认可。现在的研究揭示了核精氨酰-tRNA 合成酶在通过 SRRM2 调节可变 mRNA 剪接以响应炎症和降低的精氨酸水平方面的功能。
更新日期:2023-04-15
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