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A Role for Blood-brain Barrier Dysfunction in Delirium following Non-Cardiac Surgery in Older adults
medRxiv - Anesthesia Pub Date : 2023-05-10 , DOI: 10.1101/2023.04.07.23288303 Michael J. Devinney , Megan K. Wong , Mary Cooter Wright , Edward R. Marcantonio , Niccolò Terrando , Jeffrey N. Browndyke , Heather E. Whitson , Harvey J. Cohen , Andrea G. Nackley , Marguerita E. Klein , E. Wesley Ely , Joseph P. Mathew , Miles Berger ,
medRxiv - Anesthesia Pub Date : 2023-05-10 , DOI: 10.1101/2023.04.07.23288303 Michael J. Devinney , Megan K. Wong , Mary Cooter Wright , Edward R. Marcantonio , Niccolò Terrando , Jeffrey N. Browndyke , Heather E. Whitson , Harvey J. Cohen , Andrea G. Nackley , Marguerita E. Klein , E. Wesley Ely , Joseph P. Mathew , Miles Berger ,
Objective Although animal models suggest a role for blood-brain barrier dysfunction in postoperative delirium-like behavior, its role in postoperative delirium and postoperative recovery in humans is unclear. Thus, we evaluated the role of blood-brain barrier dysfunction in postoperative delirium and hospital length of stay among older surgery patients.
中文翻译:
血脑屏障功能障碍在老年人非心脏手术后谵妄中的作用
目的尽管动物模型表明血脑屏障功能障碍在术后谵妄样行为中起作用,但其在人类术后谵妄和术后恢复中的作用尚不清楚。因此,我们评估了血脑屏障功能障碍在老年手术患者术后谵妄和住院时间中的作用。
更新日期:2023-05-12
中文翻译:
血脑屏障功能障碍在老年人非心脏手术后谵妄中的作用
目的尽管动物模型表明血脑屏障功能障碍在术后谵妄样行为中起作用,但其在人类术后谵妄和术后恢复中的作用尚不清楚。因此,我们评估了血脑屏障功能障碍在老年手术患者术后谵妄和住院时间中的作用。