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A community Biased Signaling Atlas
Nature Chemical Biology ( IF 12.9 ) Pub Date : 2023-03-27 , DOI: 10.1038/s41589-023-01292-8
Jimmy Caroli 1 , Alibek Mamyrbekov 1, 2 , Kasper Harpsøe 1 , Sahar Gardizi 1, 3 , Linda Dörries 4 , Eshan Ghosh 1 , Alexander S Hauser 1 , Albert J Kooistra 1 , David E Gloriam 1
Affiliation  

Biased signaling gives hormones, probes or drugs distinct functional outcomes via the same receptor. The Biased Signaling Atlas ( https://BiasedSignalingAtlas.org ) provides a community hub with data and tools to advance this paradigm, which may yield safer and more potent drugs.

中文翻译:


社区偏见的信号图谱



偏向信号通过相同的受体为激素、探针或药物提供不同的功能结果。 Biased Signaling Atlas ( https://BiasedSignalingAtlas.org ) 为社区中心提供了数据和工具来推进这一范例,这可能会产生更安全、更有效的药物。
更新日期:2023-03-29
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