Sexually dimorphic age-related molecular differences in the entorhinal cortex of cognitively intact elderly: Relation to early Alzheimer's changes,Alzheimer's & Dementia

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Sexually dimorphic age-related molecular differences in the entorhinal cortex of cognitively intact elderly: Relation to early Alzheimer's changes
Alzheimer's & Dementia ( IF 13.0 ) Pub Date : 2023-03-24 , DOI: 10.1002/alz.13037
Xin-Lu Chen _{1,

2} , Jennifer Monteiro Fortes ₃ , Yu-Ting Hu _{1,

2} , Juliet van Iersel ₃ , Kang-Ning He _{1,

2} , Joop van Heerikhuize ₃ , Rawien Balesar ₃ , Dick Swaab _{2,

3} , Ai-Min Bao _{1,

2}

Affiliation

Women are more vulnerable to Alzheimer's disease (AD) than men. The entorhinal cortex (EC) is one of the earliest structures affected in AD. We identified in cognitively intact elderly different molecular changes in the EC in relation to age.

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