Background: Accumulating evidence indicates that the occurrence and development of tumors are related to the activation of oncogenes and the inactivation of tumor suppressor genes caused by epigenetic mechanisms. However, the function of serine protease 2 (PRSS2) in gastric cancer (GC) is still unknown. Our study aimed to find a regulation network involved in GC.

中文翻译：

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丝氨酸蛋白酶 2 (PRSS2) 的高表达与胃癌的侵袭、转移和增殖相关

背景：越来越多的证据表明，肿瘤的发生发展与表观遗传机制引起的癌基因的激活和抑癌基因的失活有关。然而，丝氨酸蛋白酶 2 (PRSS2) 在胃癌 (GC) 中的功能仍然未知。我们的研究旨在找到一个参与 GC 的监管网络。