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Development of a two-photon fluorescent probe for imaging hydrogen sulfide (H2S) in living cells and zebrafish
Analytical Methods ( IF 2.7 ) Pub Date : 2023-03-23 , DOI: 10.1039/d3ay00375b Chen Xu 1 , Yukun Zhang 1 , Hui Sun 1 , Jindong Ai 1 , Mingguang Ren 1
Analytical Methods ( IF 2.7 ) Pub Date : 2023-03-23 , DOI: 10.1039/d3ay00375b Chen Xu 1 , Yukun Zhang 1 , Hui Sun 1 , Jindong Ai 1 , Mingguang Ren 1
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We present a new two-photon fluorescent probe (T-HS) for the detection of H2S. With the addition of hydrogen sulfide, the absorption and fluorescence spectra of the probe show regular changes. The probe exhibited favorable properties, such as large turn-on fluorescence signal, good selectivity and low cytotoxicity. Moreover, the probe T-HS was successfully used for the fluorescence imaging of H2S in live cells and zebrafish.
中文翻译：
开发用于活细胞和斑马鱼中硫化氢 (H2S) 成像的双光子荧光探针
我们提出了一种用于检测H 2 S的新型双光子荧光探针( T-HS ) 。随着硫化氢的加入，探针的吸收光谱和荧光光谱呈现规律性变化。该探针具有良好的开启荧光信号、选择性好、细胞毒性低等优点。此外，探针T-HS已成功用于活细胞和斑马鱼中H 2 S的荧光成像。
更新日期：2023-03-23
中文翻译：
开发用于活细胞和斑马鱼中硫化氢 (H2S) 成像的双光子荧光探针
我们提出了一种用于检测H 2 S的新型双光子荧光探针( T-HS ) 。随着硫化氢的加入，探针的吸收光谱和荧光光谱呈现规律性变化。该探针具有良好的开启荧光信号、选择性好、细胞毒性低等优点。此外，探针T-HS已成功用于活细胞和斑马鱼中H 2 S的荧光成像。
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