Confirmation of the Y215H mutation in the β2-octopamine receptor in Varroa destructor is associated with contemporary cases of amitraz resistance in the United States,Pest Management Science

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Confirmation of the Y215H mutation in the β2-octopamine receptor in Varroa destructor is associated with contemporary cases of amitraz resistance in the United States
Pest Management Science ( IF 3.8 ) Pub Date : 2023-03-22 , DOI: 10.1002/ps.7461
Frank D Rinkevich ₁ , Sara Moreno-Martí ₂ , Carmen Sara Hernández-Rodríguez ₂ , Joel González-Cabrera ₂

Affiliation

The parasitic mite, Varroa destructor (Anderson and Trueman), is a leading cause of honey bee colony losses around the world. Application of miticides such as amitraz are often the primary method of Varroa control in commercial beekeeping operations in the United States. It is likely that excessive and exclusive amitraz application has led to the development of amitraz resistance in Varroa. A mutation of tyrosine at amino acid position 215 to histidine (Y215H) in the β₂-octopamine receptor was identified in putatively amitraz-resistant Varroa in the United States. This research investigated the presence of the Y215H mutation in quantitatively confirmed amitraz-resistant Varroa from the United States.

中文翻译：

证实破坏瓦螨β2-章鱼胺受体中的 Y215H 突变与美国当代双甲脒耐药病例相关

寄生螨，瓦螨（安德森和特鲁曼），是世界各地蜂群损失的主要原因。在美国商业养蜂作业中，使用双甲脒等杀螨剂通常是控制瓦螨的主要方法。过量和单独使用双甲脒很可能导致瓦螨对双甲脒产生抗药性。在美国假定对双甲脒耐药的瓦螨中，发现β ₂ -章鱼胺受体中第 215 位氨基酸酪氨酸突变为组氨酸 (Y215H) 。本研究调查了定量证实的抗双甲脒瓦螨中 Y215H 突变的存在来自美国。

更新日期：2023-03-22

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