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Photonic Bandgap Fiber Microlaser with Dual-Band Emission for Integrated Optical Tagging and Sensing
Laser & Photonics Reviews ( IF 9.8 ) Pub Date : 2023-03-10 , DOI: 10.1002/lpor.202200834
Yanqiong Wang 1 , Chaoyang Gong 2 , Xi Yang 3 , Tao Zhu 2 , Ke Zhang 4, 5 , Yun‐Jiang Rao 1 , Lei Wei 6 , Yuan Gong 1
Affiliation  

Lasers are emerging as novel photonic tags for single-cell labeling, anticounterfeiting, and encryption technology due to their narrow linewidth, high spectral multiplexing capacity, and superior stimuli-responsiveness. These laser-encoded photonic tags mostly distinguish the heterogeneity but do not yet provide both tagging and sensing of biosamples, which is highly desirable for disease screening. Here, a photonic bandgap (PBG) fiber microlaser that works as a 2D tag and an immunosensor is developed. The tubular PBG structure allows strong light–matter interaction and supports dual-band lasing in the same optical fiber, enabling massive biosample tagging and sensitive biodetection. By encoding the random resonant peaks in the short-wave band and multiplexing in the spatial domain, a 2D laser tag is generated with a large encoding capacity (>28500). Immunosensing of microalbumin is realized by using the periodic resonant peaks in the long-wave band, and a limit of detection of 0.06 ng µL−1 is achieved. This work is inspiring for the development of high-performance, multifunctional integrated devices for disease screening.

中文翻译:

用于集成光学标记和传感的具有双波段发射的光子带隙光纤微型激光器

激光由于其窄线宽、高光谱复用能力和卓越的刺激响应性,正在成为用于单细胞标记、防伪和加密技术的新型光子标签。这些激光编码的光子标签主要区分异质性,但尚未提供生物样本的标记和传感,这对于疾病筛查来说是非常需要的。在这里,开发了一种用作二维标签和免疫传感器的光子带隙 (PBG) 光纤微型激光器。管状 PBG 结构允许强烈的光-物质相互作用,并支持同一光纤中的双波段激光,从而实现大量生物样本标记和灵敏的生物检测。通过对短波段的随机共振峰进行编码并在空间域进行复用,生成具有大编码容量(>28500)。利用长波段的周期性共振峰实现微量白蛋白的免疫传感,检测限达到0.06 ng µL -1 这项工作对开发用于疾病筛查的高性能、多功能集成设备具有启发意义。
更新日期:2023-03-10
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