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Opportunities of Electronic and Optical Sensors in Autonomous Medical Plasma Technologies
ACS Sensors ( IF 8.2 ) Pub Date : 2023-03-10 , DOI: 10.1021/acssensors.2c02579
Sumyea Sabrin 1 , Debabrata K Karmokar 2 , Nemai C Karmakar 3 , Sung-Ha Hong 1 , Habibullah Habibullah 2 , Endre J Szili 1
Affiliation  

Low temperature plasma technology is proving to be at the frontier of emerging medical technologies with real potential to overcome escalating healthcare challenges including antimicrobial and anticancer resistance. However, significant improvements in efficacy, safety, and reproducibility of plasma treatments need to be addressed to realize the full clinical potential of the technology. To improve plasma treatments recent research has focused on integrating automated feedback control systems into medical plasma technologies to maintain optimal performance and safety. However, more advanced diagnostic systems are still needed to provide data into feedback control systems with sufficient levels of sensitivity, accuracy, and reproducibility. These diagnostic systems need to be compatible with the biological target and to also not perturb the plasma treatment. This paper reviews the state-of-the-art electronic and optical sensors that might be suitable to address this unmet technological need, and the steps needed to integrate these sensors into autonomous plasma systems. Realizing this technological gap could facilitate the development of next-generation medical plasma technologies with strong potential to yield superior healthcare outcomes.

中文翻译:

电子和光学传感器在自主医用等离子体技术中的机遇

事实证明,低温等离子体技术处于新兴医疗技术的前沿,具有克服不断升级的医疗保健挑战(包括抗菌和抗癌耐药性)的真正潜力。然而,需要解决血浆治疗在功效、安全性和可重复性方面的显着改进,以实现该技术的全部临床潜力。为了改进等离子治疗,最近的研究集中在将自动反馈控制系统集成到医用等离子技术中,以保持最佳性能和安全性。然而,仍然需要更先进的诊断系统来向反馈控制系统提供具有足够灵敏度、准确性和可重复性水平的数据。这些诊断系统需要与生物靶标兼容,并且也不干扰等离子体处理。本文回顾了可能适合解决这一未满足的技术需求的最先进的电子和光学传感器,以及将这些传感器集成到自主等离子体系统中所需的步骤。意识到这一技术差距可以促进下一代医用等离子技术的发展,这些技术具有产生卓越医疗效果的巨大潜力。
更新日期:2023-03-10
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