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Emerging ultrasonic bioelectronics for personalized healthcare
Progress in Materials Science ( IF 33.6 ) Pub Date : 2023-03-07 , DOI: 10.1016/j.pmatsci.2023.101110
Laiming Jiang , Jiagang Wu

Emerging ultrasonic bioelectronics (UBEs) with wearable, implantable or highly integrated forms enable continuous health monitoring and on-demand medical therapy at the point of care, far more superior than traditional ultrasonic medical procedures, and are serving as the technical basis for the state-of-art personalized medicine. However, with the rapid advances in medical ultrasonic technology, a comprehensive overview of these emerging UBEs from addressing engineering challenges in materials and device structures to targeted therapeutic cases is still lacking. Herein, we comprehensively review the recent progress in emerging UBEs, focusing on engineering methodologies and functional applications in personalized healthcare. First, the fundamentals of UBEs is briefed, followed by the latest advances in functional materials critical to the advent of emerging UBEs and the device structural designs for their wearable, implantable and multifunctional integrated applications. Next, exemplary cases of emerging UBEs in terms of their properties and diagnostic, monitoring and therapeutic functional applications based on ultrasonography and ultrasonic wireless powering and communication are highlighted and systematically discussed. Finally, current challenges and opportunities in the field to further improve accuracy, specificity, and system-level integration for personalized healthcare are outlined in detail.



中文翻译:

用于个性化医疗的新兴超声波生物电子学

具有可穿戴、植入或高度集成形式的新兴超声生物电子学(UBE)能够在护理点实现持续健康监测和按需医疗,远优于传统超声医疗程序,并正在作为国家的技术基础-最先进的个性化医疗。然而,随着医学超声技术的快速发展,仍然缺乏对这些新兴 UBE 从解决材料和设备结构方面的工程挑战到有针对性的治疗案例的全面概述。在此,我们全面回顾了新兴 UBE 的最新进展,重点关注个性化医疗中的工程方法和功能应用。首先,简要介绍 UBE 的基本原理,随后是对新兴 UBE 的出现至关重要的功能材料的最新进展,以及可穿戴、可植入和多功能集成应用的设备结构设计。接下来,重点介绍并系统地讨论了新兴 UBE 在其特性以及基于超声检查和超声无线供电和通信的诊断、监测和治疗功能应用方面的典型案例。最后,详细概述了该领域当前进一步提高个性化医疗的准确性、特异性和系统级集成的挑战和机遇。强调并系统地讨论了基于超声检查和超声无线供电和通信的监测和治疗功能应用。最后,详细概述了该领域当前进一步提高个性化医疗的准确性、特异性和系统级集成的挑战和机遇。强调并系统地讨论了基于超声检查和超声无线供电和通信的监测和治疗功能应用。最后,详细概述了该领域当前进一步提高个性化医疗的准确性、特异性和系统级集成的挑战和机遇。

更新日期:2023-03-07
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