Tetracycline antibiotics (TCs), one of the important antibiotic groups, have been widely used in human and veterinary medicines. Their residues in foodstuff, soil and sewage have caused serious threats to food safety, ecological environment and human health. Here, we reviewed the potential harms of TCs residues to foodstuff, environment and human beings, discussed the luminescence and aptamer sensors based analytical determination, adsorptive removal, and degradation strategies of TCs residues from a recent 5-year period. The advantages and intrinsic limitations of these strategies have been compared and discussed, the potential challenges and opportunities in TCs residues degradation have also been deliberated and explored.

四环素类抗生素 (TCs) 是重要的抗生素类别之一，已广泛用于人类和兽医学。它们在食品、土壤和污水中的残留已对食品安全、生态环境和人类健康造成严重威胁。在此，我们回顾了TCs残留对食品、环境和人类的潜在危害，讨论了近5年来基于发光和适体传感器的TCs残留的分析测定、吸附去除和降解策略。比较和讨论了这些策略的优势和内在局限性，还审议和探索了 TCs 残留物降解的潜在挑战和机遇。