Degradable optical resonators as in situ microprobes for microscopy-based observation of enzymatic hydrolysis,Chemical Communications

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Degradable optical resonators as in situ microprobes for microscopy-based observation of enzymatic hydrolysis
Chemical Communications ( IF 4.3 ) Pub Date : 2023-01-13 , DOI: 10.1039/d2cc05597j
Akihide Takeuchi ₁ , Wey Yih Heah ₁ , Yohei Yamamoto ₁ , Hiroshi Yamagishi ₁

Affiliation

Optical resonators work as precise physical and chemical sensors. Here, we assemble a whispering gallery mode resonator from a natural polymer, fibroin protein, and successfully observe its catalytic degradation reaction as a spectral shift. This methodology will contribute to the precise in situ observation of biological reactions by optical microscopy.

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