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Degradable optical resonators as in situ microprobes for microscopy-based observation of enzymatic hydrolysis
Chemical Communications ( IF 4.3 ) Pub Date : 2023-01-13 , DOI: 10.1039/d2cc05597j
Akihide Takeuchi 1 , Wey Yih Heah 1 , Yohei Yamamoto 1 , Hiroshi Yamagishi 1
Affiliation  

Optical resonators work as precise physical and chemical sensors. Here, we assemble a whispering gallery mode resonator from a natural polymer, fibroin protein, and successfully observe its catalytic degradation reaction as a spectral shift. This methodology will contribute to the precise in situ observation of biological reactions by optical microscopy.

中文翻译:

可降解光学谐振器作为原位微探针,用于基于显微镜的酶水解观察

光学谐振器用作精确的物理和化学传感器。在这里,我们用天然聚合物丝心蛋白组装了一个回音壁模式谐振器,并成功地观察到它的催化降解反应作为光谱位移。这种方法将有助于通过光学显微镜对生物反应进行精确的原位观察。
更新日期:2023-01-18
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